Recent studies have suggested that serum lipid levels may play a role in the development of glaucoma . However, the relationship between various lipids and glaucoma risk remains unclear. To address this gap, researchers have examined the association of high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TG) with glaucoma in a cohort of 400,229 individuals aged 40 to 69.
The study found that higher HDL-C levels were linked to an increased risk of glaucoma, while elevated levels of LDL-C, TC, and TG were associated with a reduced risk. Furthermore, genetic analysis indicated that each additional genetic risk factor for HDL-C was associated with a 5% higher risk of developing glaucoma. These findings suggest an association between lipid profiles and glaucoma risk and highlight the need for a re-evaluation…