Current guidelines recommend stopping cervical cancer screening in women aged 65 and above with a history of normal results, but the necessity of this remains debated. Given rising human papillomavirus (HPV) infection rates and cervical abnormalities in women aged 65 and above, a retrospective study analyzed data over 2.15 million screening records to assess the importance of continued screening in this population. The study found that women aged 65 and above had a higher prevalence of high-risk HPV (hr-HPV) (13.67%) compared to younger women (8.08%), with increased detection rates of cervical intraepithelial neoplasia grade 2 (CIN2+) (3.33‰ vs.
1.55‰) and cervical cancer (0.92‰ vs. 0.1‰). Single, double, and triple hr-HPV infections in this age group showed progressively higher CIN2+ risks, with odds ratios of 55.86, 65.95, and 85.45, respectively, indicating a clear dose-response…
