Synopsis Recent studies suggest that low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet can ameliorate symptoms of irritable bowel syndrome (IBS) in children. The present study highlights the efficacy of a low FODMAP diet in childhood IBS and its association with gut microbial composition. This “ MED FACT ” discusses a clinical trial from Alimentary Pharmacology and Therapeutics, “ Randomised clinical trial: gut microbiome biomarkers are associated with clinical response to a low FODMAP diet in children with the irritable bowel syndrome ”. Authors : B. P. Chumpitazi, J. L.

Cope, E. B. Hollister, C. M. Tsai, et al. Study in brief Objective: Analyzing the efficacy of a low FODMAP diet in childhood IBS and whether the gut microbial composition and/or metabolic capacity are associated with its efficacy Study Type: The randomized, double-blind, crossover…