A 73-year-old woman presented with a 1-year history of a persistent ulcer and white patch on the right margin of the tongue and soreness while eating. She did not smoke or drink alcohol. Examination Extraoral examination revealed no cervical lymphadenopathy.
Intraoral examination revealed a well-circumscribed superficial ulcer (7mm*3mm) with homogenous base, an indurated upper border, and an adjacent speckled red and white patch at the lower border (1st image) Biopsy (H & E staining) of indurated upper border was performed (as indicated in 2nd Image) Incisional biopsy of the speckled area was also performed (as indicated in 3rd image) What is the most likely diagnosis in this case? *This case is from Docplexus editorial team for education purpose only. Source: NEJM
