Case presentation:  The patient reported  chronic fatigue and aching joints, which started several months ago. He had received a  blood transfusion after a gunshot injury to his arm 35 years ago. He reports d i stal paraesthesia of both legs and painful burning in both feet, which advanced to the lower and upper limbs. Knee pain wakes him up at night .

Examination: Investigations   What is the most likely diagnosis for this patient and what would be your treatment approach for him? *This Case Challenge is from the Editorial Team of Docplexus and is meant for educational purposes only. Source: Immunopedia