Benefits of liver or organ transplantation are possible only when the graft is not rejected. Immunosuppressive therapy provides indirectly provides protection to the graft against body's immune system. This article discusses different classes of immunosuppressive agents used after liver transplantation to ensure long-term graft function while maintaining the immunity against other infections.
Due to the advancements in the surgical techniques and immunosuppressants, liver transplantation has become an extremely successful treatment for patients with end stage liver disease. The aim of the immunosuppression is to prevent the allograft function while still maintaining the immunologic control over other infections and neoplasms. Whereas the long term goal is to promote the long-term graft function without immunosuppressive therapy , while maintaining the immunity against the opportunistic…
