High-resolution typing of the human leukocyte antigen (HLA), an important molecule in induction and regulation of immune responses, enhances outcomes in advancing hematopoietic stem cell transplantation (HSCT). 1 HLA matching has been recognized as a critical factor for enhancing patient outcomes during transplantation. 2 A significant advance in the field that improves the efficiency, accuracy, and accessibility of the procedure by enabling complete full-length HLA gene typing is next-generation sequencing (NGS). 3 Here’s a graphical summary that describes the details and benefits of NGS for high-resolution HLA typing in hematopoietic stem cell transplants.

##References-Introduction## Rafiee M, Abbasi M, Rafieemehr H, Mirzaeian A, Barzegar M, Amiri V, Shahsavan S, Mohammadi MH. A concise review on factors influencing the hematopoietic stem cell transplantation main outcomes. Health…