Acute pancreatitis (AP) is an inflammatory disorder of the pancreas that can result in multiorgan failure and lead to an overall mortality of up to 20%. AP is associated with complex pathophysiologies, including calcium-mediated acinar cell injury, apoptosis, necrosis, and death. In addition, endoplasmic reticulum stress, autophagy, impaired trafficking, and intra-acinar trypsinogen activation are also hypothesized to be the primary mechanisms of pancreatitis. However, the inflammatory reactions in acute pancreatitis develop independently.
Reference: International Journal of Inflammation ##Disclaimer## The content provided on Docplexus is intended for educational purposes only. While we strive to ensure its accuracy, we make no explicit or implied warranties about the information's suitability, reliability, or adequacy, including data visualization elements and graphics. We do not…
