A 74-year-old woman had her LFTs checked routinely as part of her annual hypertension screen. Her medical history includes sciatica, hypothyroidism, mild depression and psoriasis. Her current medications include amiloride 5mg once daily, atenolol 50mg nightly, calcipotriol, furosemide 40mg once daily, sertraline 50mg once daily and levothyroxine. Case history Her LFTs revealed raised GGT and ALP of 92 and 184 units/L respectively.

Further history was taken and revealed that the patient did not drink alcohol and had never taken a statin or other medication potentially affecting her LFTs. However, she did report undergoing a blood transfusion many years ago and also thought that her mother possibly had 'liver cancer' but the details of this were unclear. The patient denied any abdominal pain and no stigmata of chronic liver disease were noted. She was a smoker and had reported some…