Polygeline improved hemodynamic stability in patients with hypovolemia following a traumatic injury and the improvement was seen within the golden hour of polygeline administration and maintained consistently reported a recent study published in the Journal of Emergency Trauma Shock. The clinical study examined the effectiveness and safety of polygeline in adult patients with hypovolemia due to traumatic injury. Polygeline was administered after evaluating the amount of blood loss and investigating the hematological and biochemical parameters. The percentage of patients administered 500, 1000, 1500, and 2000 ml polygeline were 28%, 48% 15%, and 7%, respectively.

The changes in vital signs, serum electrolytes, arterial pH, and serum lactate were continuously monitored. The safety was evaluated by recording the adverse events if any. The study reported that IV administration of polygeline…