A 21years, a young boy has acne with psoriatic transformation /or seborrhoea, obesity from childhood, High myopia --8.5D and 5D, Albino to red face, Gynocomastia ++++, congenital vitiligo patch on Abdomen and big toe. Parents also obese but normal Indian faces and features.

Look at pictures and suggest what it can be and what investigations should be ordered?