Lennox-Gastaut syndrome is a severe, childhood-onset electroclinical syndrome comprised of multiple seizure types, intellectual and behavioral impairment. Although the quality of life is severely disturbed in these patients, current therapeutic options have demonstrated significant positive patient outcomes. This article describes the effective approach for the management of Lennox-Gastaut Syndrome.
Lennox-Gastaut syndrome (LGS), or childhood epileptic encephalopathy, is a pediatric epilepsy syndrome characterized by multiple seizure types, mental retardation or regression, and abnormal findings on electroencephalography (EEG). Interictal EEG may demonstrate the following characteristics: A slow background that can be constant or transient Awake – Diffuse slow spike wave Non-REM sleep – Discharges that are more generalized and more frequent, consisting of polyspikes and slow waves REM…
