A 45-year-old man with a biopsy-proven pineal tumor was on the seventh day of his first cycle of chemotherapy when symptoms of meningeal irritation and confusion developed. Polymerase chain reaction of cerebrospinal fluid revealed herpes simplex virus type 2, and after acyclovir treatment he appeared to make a complete recovery. However, during his third cycle of chemotherapy, he had severe visual loss. Despite therapy, the patient was left with no light perception bilaterally.
What is the possible diagnosis? What is the management? *This case is from docplexus editorial team for educational purpose only.
