Merkel cell carcinoma is very rare skin disease in which malignant cells forms in the skin. Reports suggest , a high occurrence of this tumour are in the patients undergone organ transplant and who are immunocompromised . How to detect this disorder? what is the differential diagnosis? What is the pathogenesis of this disease? Let's find out in this article.
Merkel cell carcinoma(MCC) is a rare primary cutaneous neoplasm with epithelial and neuroendocrine differentiation and it has been first described by Toker in 1972 as the “trabecular carcinoma of the skin”. The reported annual incidence of Merkel Cell carcinoma (MCC) ranges from 0.2 to 0.45 per 1000003. Risk Factors: MCC predominantly affects persons with light skin. MCC is typically seen in older individuals, with the mean age at diagnosis of 76 years for women and 74 years for men. However, MCC occurs at a younger age and higher…
