The Miltenberger (Mi) classes denote a group of phenotypes for red blood cells carrying low-frequency antigens linked to the MNS blood group system. The Mi antigen (MNS7) of the MNS blood group system holds clinical significance in Asians. Anti-Mi antigen is associated with hemolytic transfusion reactions and hemolytic disease of the fetus and newborn in Thai populations, but data on this antigen frequency is limited. In recent years, with the inclusion of several new variants, a terminology based on glycophorins (Glycophorin. Vw, Glycophorin.
Hop, etc.) has replaced the original nomenclature of Miltenberger classification. A study has predicted Mi antigen frequency among southern Thai blood donors to measure the risk of alloimmunization in these populations. This is the first study to predict Mi (a+) frequencies among southern Thais. The study findings are beneficial in assessing the…
