In different cases of brain maladies, drug delivery to the brain becomes very critical. It is a very complicated process which has to consider the complex anatomy of the brain. Drug-delivery is further complicated by the intricate restrictions due to the blood-brain barrier. During the treatment of central nervous system diseases, drugs are used to treat a variety of the conditions. These drugs are usually administered through the nose.
The delivery of the drugs is hindered due to the presence of bone as well as dura/arachnoid membrane which forms the part of the blood-brain barrier. Thus, the diffusion of drugs through the blood-brain is restricted reducing the effectiveness of the drug and increased complications. The new study has published recently which uses mucosal grafts to encourage better delivery of the drugs. The study was carried out on mice and scientists think that it…
