A prospective cohort study published in Clinical Medicine Insights: Endocrinology and Diabetes evaluated the prevalence of non-thyroidal illness syndrome (NTIS) and determinants of mortality among 120 adults admitted to the medical intensive care unit (ICU) at a tertiary referral hospital in northeastern Tanzania between October 2024 and March 2025. Triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) levels were measured within 24 hours of admission, and NTIS was identified in 23.3% of patients. The overall mortality rate was 42.5%, with significantly higher mortality among patients with NTIS than those without (67.9% vs.
34.8%). After adjustment, NTIS remained independently associated with mortality (adjusted risk ratio [aRR], 8.05; 95% confidence interval [CI], 2.27–28.56; p=0.001). Patients with NTIS were also more likely to experience prolonged hospital…
