Andropause is associated with low levels of testosterone in older men. Numerous names have been given to the syndrome such as male menopause, male climacteric, androclise, androgen decline in aging male (ADAM), aging male syndrome, and late-onset hypogonadism (LOH). The andropause is characterized by nervousness, reduced potency, decreased libido, irritability, fatigue, depression, memory problems, sleep disturbances, and hot flushes.

The rate of decline in testosterone levels varies in individuals and is affected by chronic diseases such as obesity, illness, serious emotional stress, and medications; this decline can be decelerated by the management of health and lifestyle factors. How do you establish a diagnosis of late-onset hypogonadism in suspected cases?