A 64 -year-old chartered surveyor who attends emergency (A & E) department after he tripped over a paving stone whilst inspecting a site. He fell with a jolt and has had severe back pain since, prompting his hospital attendance. He also mentions that in recent weeks he has been very thirsty and has been passing urine many times at night, and he is concerned he may have diabetes.

The results of the examination are shown below: Na 138 mmol/L, K 5.5 mmol/L, Urea 26 mmol/L, Creatinine 450 μmol/L Hb 9.0 g/dL, MCV 84, WBC 5.8 × 109/L, Platelets 420 × 109 /L Glucose 4.2 mmol/L, Albumin 30 g/L, LFT NAD, cCalcium2.98 mmol/L Why does this man have polydipsia and polyuria? *This case is from Docplexus editorial team for educative purpose only Source: 100 cases in acute medicine