A prospective physiological study published in Frontiers in Physiology evaluated whether postoperative territorial arterial spin labeling (tASL) perfusion volume could serve as a non-invasive marker of cerebrovascular autoregulation failure following revascularization in adults with moyamoya disease (MMD). Key Findings The study included 116 adults with MMD who underwent combined revascularization using either the suprasylvian (n=60) or infrasylvian (n=56) approach. Cerebral hyperperfusion syndrome (CHS) occurred in 13 patients (11.2%) during hospitalization.
Hypertension and Stage IV angiographic disease were independently associated with a higher risk of postoperative CHS. Age ≥61 years and a postoperative tASL perfusion volume ≥104.45 cm³ emerged as exploratory thresholds associated with increased CHS risk. The suprasylvian approach demonstrated greater postoperative cerebral…
