A study published in PLOS Medicine examined the associations of prolonged and interrupted sedentary behavior (SB) with cancer incidence and mortality and explored the potential effects of replacing sedentary time with physical activity (PA). Study design The study included 91,292 UK Biobank participants with a mean age of 56 years. Prolonged SB was defined as any sedentary bout lasting at least 30 minutes, with at least 90% of the bout spent sedentary, whereas interrupted SB comprised sedentary bouts lasting less than 30 minutes.
Physical activity was assessed using wrist-worn accelerometers. Light PA included utilitarian movements and walking at speeds below 3 mph, moderate PA included walking at 3 to 4 mph, and vigorous PA included brisk walking at speeds above 4 mph. The study evaluated overall cancer, obesity-related and type 2 diabetes-related cancers, as well as 23 site-specific…
