An otherwise healthy 18-year old woman presented with a 2-week history of fever, malaise, and a painful left middle finger. Examination Physical examination revealed an area of erythematous, confluent vesicles associated with axillary lymphadenpathy. Clinical diagnosis of superficial skin infection (erysipelas) was made and she was started on a course of oral antibiotics. She returned 1 week later with persistent symptoms.

But similar observations were not present in her oral and genital region. What could be the most likely cause of these vesicles? *This case is from Docplexus editorial team for educative purpose only. Source: NEJM