Cervical cancer– the fourth most common cancer in women worldwide and the second most common cancer in less developed countries. India accounts for one-fourth of the world’s cervical cancer-related mortalities with almost 60,078 deaths. Systematic reviews and meta-analysis suggest that 82.7% of invasive cervical cancer show human papilloma virus (HPV) as the common risk factor . Regular cervical screening, early diagnosis, and HPV vaccination are the most effective strategies to prevent cervical cancer.
The HPV vaccine contains virus-like particles formed by HPV surface proteins and lacks genetic material (DNA). It is the most effective in eliciting an immune response but does not prevent other sexually transmitted diseases or cure an already existing HPV infection. Two vaccines are currently available in India – Gardasil and Cervarix. Both of these vaccines are manufactured using rDNA…
