A group of Swedish scientists recently demonstrated that the reduction in microRNA-210 levels in red blood cells of patients with type 2 diabetes mellitus and rodent models resulted in endothelial dysfunction. Replenishing the microRNA-210 levels in red blood cells could be the key to preventing endothelial dysfunction. Vascular injury is one of the common complications associated with type 2 diabetes mellitus (T2DM). Vascular damage in diabetes stems from endothelial dysfunction. However, the exact underlying causes of vascular damage still elude researchers.
A recent study provides insights into the mechanism behind endothelial dysfunction that involves small molecule microRNA-210 in red blood cells (RBCs). microRNA-210 plays a role in the functioning of endothelial cells. Researchers collected whole blood samples from 36 patients with T2DM and 32 healthy subjects. They incubated the…
