A 19-year-old student presents with an 18-month history of progressive tiredness, weight loss, and lethargy. One year before presentation she had a common cold that forced her to stay away from lectures for 2 days. Three months before presentation, another common cold laid her low for almost 2 weeks, during which time she lost 3 kg in weight. The local student health doctors had assured her that the symptoms were the result of either being pregnant or taking drugs.

On examination, she was noted to have darker skin than her mother and pigmented palmar creases. What would be the likely diagnosis for this case? What steps should be taken for initially managing this condition? *This case is from the Docplexus Editorial Team and is for educative purpose only.