The effective provision of safe and adequate procedural sedation is a core skill of an emergency physician. Propofol, ketamin, and ketofol are commonly used as sedative agents in emergency medicine. This article reports the study observations which determined whether emergency physician – provided deep sedation with 1:1 ketofol versus propofol resulted in fewer adverse respiratory events. Sedation and analgesia facilitates the surgeries to be conducted in a humane and in an effective manner.
Propofol and ketamine are commonly used as sedative agents in ED, but each has its advantages and disadvantages. Propofol is associated with hypotension, loss of airway reflexes, hypoventilation, apnea, and hypoxia but has an effective antiemetic and amnestic properties. On the other hand, ketamine causes hypertension and tachycardia, as well as vomiting and emergence delirium, but maintains airway…
