Proton pump inhibitors (PPIs) are prescribed for the alleviation of gastroesophageal reflux disease and peptic ulcers and usage has been tremendously increased in geriatrics. In the present study, researchers aimed to investigate the association of PPIs usage with the risk of dementia. Study Design: Prospective, longitudinal, multicenter cohort study was carried out in elderly primary care patients.
Inclusion criteria comprised of age (75 years or older), no history of dementia. Methods Diagnosis of dementia is considered if it was reported at least 2 of 6 quarters of an 18-month interval. PPI use was defined as per the prescription in each quarter of an interval, and no use was considered as no prescription in an…
