Sacroiliitis, inflammation of the sacroiliac joint, is the hallmark of ankylosing spondylitis and spondyloarthritis. The current recommended diagnostic modalities for imaging of the SIJ are limited and mostly include conventional X-rays and magnetic resonance imaging. This article discusses advanced radionuclide imaging modalities for the diagnosis of sacroiliitis in patients with spondyloarthritis.

Presently, available methods for the imaging of sacroiliac joints (SIJ) are limited. Conventional radiography lacks sensitivity, particularly at the early stages of sacroiliitis. Recent research findings implicate that bone scintigraphy, particularly single-photon emission computed tomography (SPECT) with the calculation of indices, or SPECT in combination with low-dose CT can be a sensitive and specific tool for the diagnosis of sacroiliitis and can be used as part of the individualized…