Presentation: A 57 year male was admitted with fungal infection of the eye. Medical History: Vasculitis, HTN, bronchiectasis Medications: Cyclosporine, prednisone, lisinopril Physical examination: VSS Eye: Red and painful left eye, decreased vision Chest: CTA (B) CVS: Clear S1S2 Abdomen: Soft, NT, ND, + BS Extremities: no c/c/e Laboratory results: WNL The infectious disease consultant recommends treatment with Amphotericin B which is started. The next day, the patient's creatinine has increased considerably (see attached report).
What can be the cause? How can it be managed?
