Bacterial meningitis is a significant burden of disease and mortality in all age groups worldwide despite the development of effective conjugated vaccines. The pathogenesis of bacterial meningitis is based on complex and incompletely understood host-pathogen interactions. This article describes the risk factors associated with community-acquired bacterial meningitis. Bacterial meningitis is an inflammation of the meninges and subarachnoid space that can also involve the brain cortex and parenchyma.
It is a life-threatening infectious disease with high mortality and disability rates. Meningitis can be acquired spontaneously in the community, through community-acquired bacterial meningitis or in the hospital as a complication of invasive procedures or head trauma. Despite advances in treatment and vaccinations, community-acquired bacterial meningitis remains one of the most important…