Non-alcoholic Fatty Liver Disease (NAFLD) is the most prevalent liver disease affecting 30% of the global population, with no FDA-approved treatment available currently. It is known that hepatic inflammation leads to the progression of NAFLD and B-cells are the critical regulators of immune responses. However, the activation process of B-cells in NAFLD is not clearly understood. This World Liver Day, we share an article on the role of B-cells in the development of NAFLD.
According to a study published in the journal Hepatology , B-cells play a key role in the development of NAFLD. The study was conducted at the University of Minnesota Medical School, US, after noticing that patients with NAFLD had elevated disease-fighting B-cells in their livers. Key findings of the study: Intrahepatic B-cells were elevated in people with NAFLD. Intrahepatic B-cells displayed a pro-inflammatory gene…
