Accurate assessment of insulin levels typically requires blood sampling, making the detection of hyperinsulinemia costly and invasive. To explore a non-invasive alternative, a recent study investigated saliva insulin responses to a standardized meal tolerance test in 94 healthy, normoglycemic individuals across different BMI categories. Participants fasted for at least four hours before consuming a standardized liquid meal. Saliva and blood samples were collected at baseline, 60 minutes, and 90 minutes post-meal.
Across all time points, individuals with obesity showed significantly higher saliva insulin levels than those who were overweight or of normal weight. Similarly, overweight individuals had higher levels than those of normal weight. In contrast, fasting and post-meal glucose levels did not differ significantly among the groups. These results suggest that saliva insulin…
