Synopsis   According to a recent study, elevated amount of alpha-fetoprotein (AFP) in vaginal blood as compared to that in maternal serum might be an indication of confirming a failed pregnancy. This week's ' MED FACT ' discusses a clinical trial from Fertility and Sterility, “ Same-Day Confirmation Of Intrauterine Pregnancy Failure In Women With First- And Early Second-Trimester Bleeding ”. 2018. Authors : Mor A. et al.

Key Takeaways If AFP vaginal blood /AFP maternal serum ratio is high, the higher is the possibility of IUP failure. Objective Study Type Participants To determine if alpha-fetoprotein (AFP) concentration in vaginal blood, in the setting of dissolved fetal tissue, is significantly higher than its concentration in the maternal serum. Prospective cohort study 78   What Was The Need For This Study? It is difficult to differentiate in between Intra and Extra Uterine…