A 49-year-old man visited the neuromuscular clinic with the diagnosis of amyotrophic lateral sclerosis (ALS) for a second opinion. History The patient complained to his primary doctor about a "funny feeling" in his right lower extremity, of which he first noticed 1 year ago. Sometimes his leg feels numb and sometimes he experiences mild tingling. He occasionally walks with a slight limp. He denies muscle twitching or atrophy. He can climb up and down stairs normally and has no complaints in regard to his upper extremities.
He works full-time and is independent in activities of daily living. He denies fever, weight loss, shortness of breath, chest pain, nausea, or vomiting. He has experienced no bowel, bladder, swallowing, or sexual dysfunction. Past medical history: Hypercholesterolemia. Social history: No history of smoking, alcohol or drug abuse. Family history: His sister carries the…