A forty-year-old man with quadriplegia and neurogenic bladder was admitted to the hospital. The patient had vomiting fever and cloudy urine. A yr ago the pt. had developed urticaria, wheezing, and hypotension within an hour after his first dose of nafcillin. Subsequently his penicillin skin test was positive.
During the current admission the physician noted fever quadriplegia and chronic indwelling bladder catheter. Laboratory tests revealed leukocytosis in blood and urine. Urine stain showed gram-negative rods and urine culture grew P. Aeruginosa.Which of the following drugs would be most appropriate for the pt. Ampicillin- Sulbactam Aztreonam Cefazolin Imipenem-cilastatin Piperacillin-Tazobactam.
