Spinal Muscular Atrophy (SMA) is a leading genetic cause of deaths in infants. This disease affecting motor neurons of spinal cord, brain stem is a leading genetic disease causing infant mortality. No effective treatment is available to cure the disease. Current article deals with the Spinal Muscular Atrophy, genetic neurodegenerative disease. Introduction Spinal muscular atrophy is an autosomal recessive neurodegenerative disease characterized by degeneration of spinal cord motor neurons, atrophy of skeletal muscles, and generalized weakness.
This genetic disease causes widespread mortality among infants. No effective treatment is available for this disease. With the discovery of underlying genetic causes and advent of technology, there is considerable progress in the management of the disease. Causes Deficiency of the survival motor neuron (SMN) protein - the hallmarks of which are…
