Dr. David Gladstone et al from Canada note that in CTA in patients with intracerebral hemorrhage spotting a 'spot' sign in CT angiography, as a peripheral enhancement of haematoma is not going to help on the selection of patients for the approved use of intravenous recombinant factor VII Within a time window of up to 6.5 hours. The average voulme of expansion was less than 2.5 ml with or without factor VII administration. So the SPOT sign, for the time being, can't be used to predict the outcome of ICH patients at 6 months with hemostatic therapy.

Have you ever looked for this sign? Share your anecdotal on such ICH cases.