Key Takeaways: - Cardiovascular diseases (CVDs) are a major cause of global deaths, and conventional therapies have limitations in treating CVDs. - Stem cell-based therapy using mesenchymal stem cells (MSCs) and their secretome shows promise in cardiac regeneration. - The secretome of MSCs, which includes paracrine factors and extracellular vesicles, plays a critical role in promoting cardiac repair and improving heart function.
Summary: Cardiovascular diseases (CVDs) are responsible for a significant number of global deaths, and the effectiveness of conventional therapies for CVDs is limited. Stem cell-based therapy using mesenchymal stem cells (MSCs) and their secretome is emerging as a promising alternative for cardiac regeneration. MSCs possess unique characteristics, including self-renewal capacity, multilineage differentiation potential, lack of immunogenicity, and…
