Parkinson’s disease represents a growing health concern for an ever-aging population. While genetic risks have been identified, environmental factors and gene-environment interactions probably account for most PD cases. Prevalence Neurodegenerative amyloid disorders, including Alzheimer’s, Huntington’s, and Parkinson’s diseases (PD), are each associated with a distinct amyloid protein. PD is the second most common neurodegenerative disease in the United States, affecting an estimated 1 million people and 1% of the US population over 60 years of age.
Worldwide, about 3 million patients and caregivers suffer from the often- debilitating symptoms of PD, which involve motor deficits including tremors, muscle rigidity, bradykinesia, and impaired gait. It is a multifactorial disorder that has a strong environmental component, as less than 10% of cases are hereditary. Synuclein: the culprit…
