The support of renal function in modern times involves an array of clinical scenarios. The ability to routinely deliver ongoing organ support in the outpatient setting have gained significance for organ support. Renal replacement therapy (RRT) can be applied continuously using extracorporeal or paracorporeal methods. This article emphasizes on this therapy used for supporting renal function. Artificial support of the functions of failing organs has a history deeply rooted in the beginning of the last century.
However, continuous therapies of today have their origins in the 1960s, with early descriptions of pump-assisted continuous arteriovenous hemofiltration (CAVH). Physiology RRT employs only two physiologies for solute and fluid movement. Both methods require sequestration of blood on one side of a semi-permeable membrane. In diffusive clearance (Dialysis), solute moves down its…
