Recent research published in Alzheimer's & Dementia looked at whether tadalafil, a drug similar to sildenafil, may help persons with vascular dementia. The researchers ran a Phase II trial to see if tadalafil improves brain blood flow in older men and women who have Intracranial stenosis, which can lead to strokes and vascular dementia. Dementia is a growing global health problem, affecting 55 million people now and is expected to rise to 139 million by 2050.
As fewer treatment choices are available to patients, the current study looked at whether repurposing an existing drug, tadalafil, to treat vascular dementia. Vascular dementia is a prevalent condition marked by the restricted blood supply to the brain. Sildenafil and vardenafil, medicines routinely used to enhance blood flow in erectile dysfunction and pulmonary hypertension, were found as viable candidates for preventing or…
