Vestibular schwannomas (VS) are the benign nerve sheath tumors that originate from Schwann cells of the superior and inferior vestibular part of the VIIIth cranial nerve. VS cells show high COX-2 expression compared with healthy Schwann cells. Cyclooxygenase–2 (COX-2) overexpression serves as a prominent molecular target for the treatment of VS which can be dealt with NSAIDS. Several studies reported that Aspirin has a potential therapeutic role in halting the growth of VS.
But in the present study, researchers reported the inefficiency of Aspirin in the reduction of VS growth. Study design: Retrospective, observational case-control methodology was adopted. By the determination of MRI scan, two groups were made to compare Aspirin exposure in patients with growing VS and patients with stable VS where tumor size was considered at least 2 mm. Determination of Aspirin exposure was carried…
