Objective Lower incidences of cardiovascular mortality and morbidity in overweight/obese patients compared ‘normal’ BMI subjects have been reported. We evaluated the relationship between BMI and coronary atherosclerosis in an asymptomatic cohort of patients with diabetes. Research Design and Methods 226 asymptomatic patients with type-2 diabetes and no known coronary artery disease were recruited. All patients underwent CT coronary angiograms (CTCA) at baseline.

Results There were 58.3% males with median BMI of 28.3 (IQR: 25.3-32.4), and median duration of diabetes of 13 years (IQR: 8-19). 55.5% of the study population were south Asians, reflecting their high prevalence in the catchment areas of the clinics. Four BMI categories, defining normal BMI (18-25 kgs/m 2 , overweight (25 – 30 kgs/m 2 ), obese (30-35 kgs/m 2 ) and grossly obese (>35 kgs/m2) individuals were created. In patients…