Thrombectomy performed after 6 to 24 hours from onset of symptom is beneficial in patients with acute stroke having clinical deficit that is disproportionately severe relative to the infarct volume, shows the findings of a study published in The New England Journal of Medicine. In patients with acute stroke, previous studies have shown that endovascular thrombectomy had a clinical benefit when it was performed within 6 hours after the onset of stroke symptoms and that the benefit diminished as the interval between the time of stroke onset and thrombectomy increased.
There is limited data on the efficacy of thrombectomy that is performed more than 6 hours after onset of symptoms, particularly among patients with ischemic brain tissue that has not yet undergone infarction and may be salvaged with reperfusion. DAWN (DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and…