Surgical antimicrobial prophylaxis (SAP) is recommended for various procedures to prevent surgical site infection (SSI). To maximize the effect of prophylaxis, it is recommended that it is administered 30 to 60 minutes before the surgical incision. However, the precise optimum timing is unknown. The study reported in this article compared early versus late administration of SAP before surgery.
Surgical site infections (SSI) are the most common hospital-acquired infections in surgical patients. Surgical antimicrobial prophylaxis (SAP) is recommended 30 to 60 minutes to reduce the toxicity and antimicrobial resistance and to reduce cost. Single shot first generation or second generation cephalosporins are widely used as the drug of choice for routine SAP. Generally, SAP is recommended when a high rate of postoperative wound infection or when foreign material is implanted, or when the…
