Coagulopathy accompanying with trauma occurs in one-third of all severely injured patients upon presentation to the hospital. Trauma patients presenting with coagulopathy have significantly higher mortality. A combination of endogenous biological processes can lead to the lethal triad of hypothermia, academia in trauma-induced coagulopathy. Globally trauma and associated hemorrhage are a major cause of shock and mortality.
Massive hemorrhage induced by trauma-induced coagulopathy exists in nearly one-third of all severely injured trauma patients and is responsible for 50 % mortality rate. Trauma-induced coagulopathy: Clot formation is a complicated process that requires multiple events and variables to produce a stable clot. Under normal conditions, clot formation reduces blood loss and assists with the return of hemostasis. Massive injury can disrupt the clotting cascade at several…
