Autoimmune hepatitis is a chronic disease of unknown cause and is characterized by continuing hepatocellular inflammation and necrosis and has a tendency to progress to cirrhosis. I had experienced a case, sharing with you. A 39-year-oldd female, with a history of progressive painless jaundice of 2 weeks duration without any viral prodrome or offending drug intake. On examination, she was conscious, oriented and icteric. Her vitals were stable.

Her physical examination was unremarkable. Laboratory tests reports: Normal hemogram but erythrocyte sedimentation rate (ESR) was raised at 52 mm/H (normal, 0-20 mm/H). She had an elevated INR 2.7. Liver function tests reports: Predominantly conjugated hyper bilirubinemia [Bilirubin 8 mg/dl )] and elevated liver enzymes (AST aspartate aminotransferase: 818U/L and ALT 51 5 U/L). Serum alkaline phosphatase levels were also elevated at 327 IU/L /L.…