A 74 year�old female has complains of abdominal pain and altered bowel habitus for two months. She has no comorbidities, no significant past history except for hysterectomy 25 yrs back. She underwent USG which showed rectal lesion and was further suggested for CT scan. On CT scan she has a rectal mass at 8 cm from anal verge, about 4.5 cm in length without luminal compromise with multiple enlarged bilateral external iliac nodes. For nodal issue, an MRI pelvis with contrast was done which confirmed the findings in addition to a left para aortic node which was 3 cm in max diameter.

A PET CT was done which confirmed the local disease with para aortic node having standardised uptake value SUV max of 7. She was subjected to colonoscopy for biopsy and biopsy was sent for K-ras evaluation which is wild type. She was given two cycles of FOLFOX with Panitimumab. And now she is been taken for…