Neurological disorders present an increasing challenge for an ageing population and the focus remains on pharmacological interventions for confirming or eliminating the condition. Setbacks in clinical trials and the obstacle of access to the brain for drug delivery and surgery have highlighted the potential for therapeutic use of ultrasound in neurological diseases. The current article has been adopted from a review published in a renowned journal and discusses milestones in the development of therapeutic ultrasound.
The article provides an overview of the principles of diagnostic and therapeutic ultrasound, for surgery and transient opening of the blood–brain barrier, and its application in clinical trials of stroke, Parkinson disease and chronic pain. and the technology has proved useful for inducing focused lesions, clearing protein aggregates, facilitating drug uptake, and…
