Vitamin D has effects on a variety of systems including immune, cardiovascular and nervous system. Deficiency of vitamin D is a common problem among patients with chronic kidney disease (CKD). Serum levels of vitamin D compounds decline. This is associated with an increased morbidity and mortality among patients with CKD. A disproportionately high number of patients with chronic kidney disease have the deficiency of vitamin D.
The deficiency is also seen in patients undergoing dialysis. The significant role of vitamin D in several key functions of the body implies an increased morbidity and mortality in patients with renal disease. Vitamin D executes numerous regulatory functions in the body. Vitamin D is classically involved in maintaining the integrity of the skeletal structure and serum levels of calcium and phosphates. Nonclassical or peripheral autocrine functions of vitamin D…
